Toxic Release Inventory (TRI) Chemicals

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Product name

CAS

Formula

Alpha-Methyl Styrene

CAS98-83-9

FormulaC9H10/C6H5C(CH3)=CH2

Synonym1-Methyl-1-phenylethene, Benzene, (1-methylethenyl)-

n-Propyl benzene and styrene in total, wt pct0.03% max

Density0.9062

Refractive index nD at 20°C1.5382 - 1.5392

Colour10 max

Alpha-methyl Styrene, wt pct99.7% min

Phenol, wt pct0.0015% max (with stabilizer)

Pnenol, wt pct0.0005% max (without stabilizer)

Colorcolorless liquid

Refractive Index1.5359

Insolubilityin water

Molecular weight118.19

Flash Point53.9 c

Boiling Point164-165 c

Tetracycline HCI

CAS64-75-5

FormulaC22H 24N 2O 8·HCl

Synonym2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-

Potency900 µg of C22H24N2O8·HCl per mg

IdentificationTo pass IR and UV test

Crystallinitymeets the requirements

pH1.8 - 2.8

Specific Rotation-240° to -255°

Loss on Dryingnot more than 2.0%

Heavy Metals0.005% max

Tamoxifen Citrate

CAS54965-24-1

FormulaC26H 29NO·C 6H 8O 7

Synonym(Z)-2-[ p-(1,2-Diphenyl-1-butenyl)phenoxy]- N, N-dimethylethylamine citrate (1:1)

Assay99.0 - 101.0 %

Heavy Metals0.001%

Loss on Dryingnot more than 0.5%

IdentificationTo pass IR and UV test

Residue on Ignitionnot more than 0.2%

Tretinoin - Retinoic Acid

CAS302-79-4

FormulaC20H28O2

SynonymAll-trans-retinoic acid, Retinoic acid

Assay97.0 - 103.0 %

Loss on Dryingnot more than 0.5%

IdentificationTo pass IR and UV test

Residue on Ignitionnot more than 0.1%

Heavy Metals0.002% max

Progesterone

CAS57-83-0

FormulaC21H30O2

SynonymPregn-4-ene-3,20-dione

Related SubstancesTotal impurity: 0.8% Max.

Assay97.0% - 103.0%

Specific Rotation+186° to 194° (BP)

Melting Point126°C to 131°C (USP)

AppearanceWhite or almost crystalline powder (micronized)

Related SubstancesIndividual impurity: 0.5% Max.

Specific Rotation+175° to 183° (USP)

Melting Point128°C to 132°C (BP)

Assay97.0% - 103.0%

Melting Point128°C to 132°C (BP)

Loss on Drying0.5% Max.

Related SubstancesTotal impurity: 0.8% Max.

Related SubstancesIndividual impurity: 0.5% Max.

Specific Rotation+186° to 194° (BP)

Specific Rotation+175° to 183° (USP)

Melting Point126°C to 131°C (USP)

Loss on Drying0.5% Max.

Primidone

CAS125-33-7

FormulaC12H 14N 2O 2

Synonym5-Ethyldihydro-5-phenyl-4,6(1H,5 H)-pyrimidinedione

IdentificationTo pass IR and UV test

Organic Volatile Impuritiesmeets the requirements

Melting Range279? - 284?C

Assay98.0 - 102.0%

Loss on Dryingnot more than 0.5%

Residue on Ignitionnot more than 0.2%

Metronidazole

CAS443-48-1

FormulaC6H 9N 3O 3

Synonym2-Methyl-5-nitroimidazole-1-ethanol

Residue on Ignitionnot more than 0.1%

IdentificationTo pass IR and UV test

Melting Range159° - 163°C

Assay99.0 - 101.0%

Heavy Metals0.005% max

Loss on Dryingnot more than 0.5%

Methoxsalen

CAS298-81-7

Formula298-81-7

Synonym9-Methoxy-7H-furo[3,2- g][1]benzopyran-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-

Assay98.0 - 102.0%

IdentificationTo pass IR test

Melting Range143° - 148°C

Water Contentnot more than 0.5%

Residue on Ignitionnot more than 0.1%

Heavy Metals0.002%

Organic Volatile Impuritiesmeets the requirements

Hydroquinone

CAS123-31-9

FormulaC6H4(OH)2

SynonymBenzene-1,4-diol, 1,4-Benzenediol, Hydroquinone

Density1.330

Auto/Self Ignition Temperaturetemp. 516 c

Slightly Solublein benzene

Moderately Solublein acetone

SolubleSoluble 7g/100ml in water.

Specific Gravity (20°C)1.35 @20°C

Vapor Pressure.1 mmHg @ 60°C

Assay %99% Min

Melting Point170.5 °C Min

Auto Ignition Temp930°F

Water when shipped0.3% Max

Flash Point COC °C165°C

Dropping Point285°C

Residue on Ignition0.3% Max

Vapor Density3.81

SensoricOff white or slight yellow crystalline powder.

pHweakly acidic (aq. solns.)

Colordiscolored by light and air

Odorodorless

Molecular weight110.11

Flash Point(tcc) 165 c

Solubilitywater, alcohol, ether, ccl4, oxygenated solvs.

Boiling Point285 c

Haloperidol

CAS52-86-8

FormulaC21H 23ClFNO 2

Synonym4-[4-(p-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone

Assay98.0 - 102.0%

IdentificationTo pass Ir and Uv test

Melting Range147° - 152°C

Loss on Dryingnot more than 0.5%

Residue on Ignitionnot more than 0.1%

Organic Volatile Impuritiesmeets the requirements

Flutamide

CAS13311-84-7

FormulaC11H 11F 3N 2O 3

Synonyma,a,a-Trifluoro-2-methyl-4'-nitro- m-propionotoluidide

Assay98.0 - 101.0%

IdentificationTo pass IR test

Melting Range110° - 114°C

Loss on Dryingnot more than 1.0%

Residue on Ignitionnot more than 0.1%

Heavy Metalsnot more than 10 ppm

Estrone

CAS53-16-7

FormulaC18H 22O 2

Synonym3-Hydroxyestra-1,3,5(10)-trien-17-one, Estra-1,3,5(10)-trien-17-one, 3-hydroxy-

Assay97.0 - 103.0%

IdentificationTo pass IR and UV test

Specific Rotation+158° to +165°

Loss on Dryingnot more than 0.5%

Residue on Ignitionnot more than 0.5%

Diazoxide

CAS364-98-7

FormulaC8H 7ClN 2O 2S

Synonym7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Assay97.0 - 102.0%

IdentificationTo pass IR test

Loss on Dryingnot more than 0.5%

Residue on Ignitionnot more than 0.1%

Cyclosporin

CAS59865-13-3

FormulaC62H 111N 11O 12

SynonymCyclosporin A

Assay98.5 - 101.5%

Loss on Dryingnot more than 2.0%

Heavy Metals0.002% max

Danazol

CAS17230-88-5

FormulaC22H 27NO 2

Synonym17a-Pregna-2,4-dien-20-yno[2,3- d]isoxazol-17-ol

Assay97.0 - 102.0%

IdentificationTo pass IR and UV test

Specific Rotation+21° to +27°

Loss on Dryingnot more than 2.0%

Organic Volatile Impuritiesmeets the requirements

Cyclophosphamide

CAS50-18-0

FormulaC7H 15Cl 2N 2O 2P

Synonym(±)-2-[Bis(2-chloroethyl)amino]tetrahydro-2 H-1,3,2-oxazaphosphorine 2-oxide

Assay97.0 - 103.0%

IdentificationTo pass IR test

pH3.9 - 7.1

Water Content5.7% - 6.8%

Heavy Metals0.002% max

Carbamazepine

CAS298-46-4

FormulaC15H 12N 2O

Synonym5H-Dibenz[ b, f]azepine-5-carboxamide

Assay98.0 - 102.0%

IR Identificationmeets the requirements

Residue on Ignitionnot more than 0.1%

Chloride0.014% max

Heavy Metals0.001% max

Loss on Dryingnot more than 0.5%

Amikacin Sulfate

CAS39831-55-5

FormulaC22H 43N 5O 13·H 2SO 4

SynonymAmikacin

Identificationmeets the requirements

Specific Rotationbetween +76° and +84°

Crystallinitymeets the requirements

pH6.0 - 7.3

Loss on Dryingnot more than 13.0%

Residue on Ignitionnot more than 1.0%

Amantadine Hydrochloride

CAS665-66-7

FormulaC10H 17N·HCl

SynonymAmantadine HCl, Tricyclo[3.3.1.13,7]decan-1-amine, hydrochloride (1:1)

Assay98.5 - 101.5%

IR Identificationmeets the requirements

pH3 - 5.5

Heavy Metalsthe limit is 0.001%

Organic Volatile Impuritiesmeets the requirements

Acetazolamide

CAS59-66-5

FormulaC4H6N4O3S2

SynonymN - (5 - Sulfamoyl - 1,3, 4 - thiadiazol - 2 - yl) acetamide, Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-

Assay98 - 102%

IR Identificationmeets the requirements

Water Contentnot more than 0.5%

Residue on Ignitionnot more than 0.1%

Chloridesnot more than 0.014%

Sulfatesnot more than 0.04%

Selenium0.003%

Heavy Metals0.002%

Organic Volatile Impuritiesmeets the requirements

Sodium Lauryl Sulfate

CAS151-21-3

FormulaCH3(CH2)10CH2OSO3Na

SynonymSDS, SLS, Sulfuric acid monododecyl ester sodium salt (1:1), Sodium dodecyl sulphate

Anionic Activespt(mw 296) 27.5 -28.5

pH of 10% water solution7.5-8.5

NaCl0.3 Max

Na2SO40.3 Max

Unsulfated Matter0.5 Max

Foreign Matters (-0.2-0.9 mm)0.03 - 0.05

Color, APHA; ASTM D 120950 max

Viscocity500cps Max

Sulfite(strip test) Negative

Preoxide(strip test) Negative

Specific gravity1.08

Density8.84 lbs/gal

Copper Ascorbate Blend 6% 40M

CAS7440-50-8

FormulaC6H8CuO10S

SynonymCOPPER, Copper

Colorcopper-colored porous powder

Specific gravity8.0

Chromium Molybdenum Trituration 1% 60 Mesh

CAS7440-47-3

FormulaCr

SynonymCHROMIUM

Density7.1

Insolubilityin water

Melting Point1900 c

Solubilityacids (except nitric) and strong alkalis

Boiling Point2200 c

Chromium Yeast 0.2% Blend Only

CAS7440-47-3

FormulaCr

SynonymChromium

Density7.1

Insolubilityin water

Melting Point1900 c

Solubilityacids (except nitric) and strong alkalis

Boiling Point2200 c

Chromium Yeast Dark

CAS7440-47-3

FormulaCr

SynonymCHROMIUM

Density7.1

Insolubilityin water

Melting Point1900 c

Solubilityacids (except nitric) and strong alkalis

Boiling Point2200 c

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