Calcium Folinate, USP
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(914) 654-6800or email 
INFO@PARCHEM.COM
(914) 654-6800
INFO@PARCHEM.COM
For more informationemailINFO@PARCHEM.COM
email
INFO@PARCHEM.COM
Product Description
Product
Calcium Folinate, USP
CAS
1492-18-8
Formula
C20H 21CaN7O7
Synonym
Leucovorin Calcium
Typical Product Specifications
Purity Test, 5-formyltetrahydropteoric acid
NMT 1.0%
Absorbance (420nm)
NMT 0.60
Purity Test 7,8-dihydrofolic acid
NMT 1.0%
Water Content (by Karl Fischer)
NMT 17.0%
Sieve analysis, particles<100 um
NLT 80%
Sieve analysis, particles>200 um
NMT 10%
Tapped Density
0.45 - 0.75 g/ml
Optical rotation, 2.5% in H2O
14.4-18.0°
Purity Test, 10-formylfolic acid
NMT 1.0%
Appearance of solution (2.5 aqueous solution)
Clear
Appearance
White to light yellow powder
Sum impurities
NMT 2.0%
Loose Density
0.20 - 0.50 g/ml
Total Aerobic Microbial Count
NMT 500 cfu/g
Heavy Metals
NMT 50ppm
Bacterial endotoxins (LAL test)
NMT 0.350EU/mg
IR spectrum
Comparable to reference spectrum
Purity Test, p-aminobenzoylglutamic acid
NMT 1.0%
Residual methanol
NMT 0.3%
Purity Test, folic acid
NMT 1.0%
Purity Test, Individual unidentified impurities
NMT 0.1%
Chlorides
NMT 0.5%
Purity Test, 10-formyltetrahydrofolic acid
NMT 1.0%
Total molds and yeast
NMT 100 cfu/g
Platinum
NMT 20ppm
Purity Test 5,10-diformyltetrahydrofolic acid
NMT 1.0%
pH (2.5% aqueous solution)
6.8-8.0
Color value (1% aqueous solution)
NMT 250 APHA
Residual ethanol
NMT 0.5%
Assay, Calcium Folinate (by HPLC)
97.0 - 102.0%
Assay, Calcium
7.54 - 8.14%
Residual acetone
NMT 0.5%
Notes
Store at up to 25C in an airtight container. Do not freeze.
Class
Calcium Folinate, USP
For more information call (914) 654-6800or email INFO@PARCHEM.COM
(914) 654-6800
INFO@PARCHEM.COM
For more informationemailINFO@PARCHEM.COM
email
INFO@PARCHEM.COM
Product Description
Product
Calcium Folinate, USP
CAS
1492-18-8
Formula
C20H 21CaN7O7
Synonym
Leucovorin Calcium
Typical Product Specifications
Purity Test, 5-formyltetrahydropteoric acid
NMT 1.0%
Absorbance (420nm)
NMT 0.60
Purity Test 7,8-dihydrofolic acid
NMT 1.0%
Water Content (by Karl Fischer)
NMT 17.0%
Sieve analysis, particles<100 um
NLT 80%
Sieve analysis, particles>200 um
NMT 10%
Tapped Density
0.45 - 0.75 g/ml
Optical rotation, 2.5% in H2O
14.4-18.0°
Purity Test, 10-formylfolic acid
NMT 1.0%
Appearance of solution (2.5 aqueous solution)
Clear
Appearance
White to light yellow powder
Sum impurities
NMT 2.0%
Loose Density
0.20 - 0.50 g/ml
Total Aerobic Microbial Count
NMT 500 cfu/g
Heavy Metals
NMT 50ppm
Bacterial endotoxins (LAL test)
NMT 0.350EU/mg
IR spectrum
Comparable to reference spectrum
Purity Test, p-aminobenzoylglutamic acid
NMT 1.0%
Residual methanol
NMT 0.3%
Purity Test, folic acid
NMT 1.0%
Purity Test, Individual unidentified impurities
NMT 0.1%
Chlorides
NMT 0.5%
Purity Test, 10-formyltetrahydrofolic acid
NMT 1.0%
Total molds and yeast
NMT 100 cfu/g
Platinum
NMT 20ppm
Purity Test 5,10-diformyltetrahydrofolic acid
NMT 1.0%
pH (2.5% aqueous solution)
6.8-8.0
Color value (1% aqueous solution)
NMT 250 APHA
Residual ethanol
NMT 0.5%
Assay, Calcium Folinate (by HPLC)
97.0 - 102.0%
Assay, Calcium
7.54 - 8.14%
Residual acetone
NMT 0.5%
Notes
Store at up to 25C in an airtight container. Do not freeze.
Class
